Drug Standards
Medchemexpress LLC Metoclopramide | 364-62-5 | 99.9% | 299.80 | 1 ML
Metoclopramide is a potent antagonist of 5-HT3 and dopamine D2 receptors, with IC50s of 308 nM and 483 nM, respectively. It can be used for the research of nausea and vomiting, gastro-oesophageal reflux, and gastroparesis.
- Potent antagonist of 5-HT3 and dopamine D2 receptor
- Used for research of nausea and vomiting, gastro-oesophageal reflux, and gastroparesis
Medchemexpress LLC Doramectin (Standard) | 117704-25-3 | 97.4% | 899.11 | 25 MG
Doramectin (Standard) is the analytical standard of Doramectin, intended for research and analytical applications. It is a derivative of Ivermectin and acts as a potent antiparasitic antibiotic. This compound is active against *S. mansoni* in an NMRI mouse infection model and is used as a reference for various assays.
- Analytical standard for research and analytical applications.
- Derivative of Ivermectin.
- Potent antiparasitic antibiotic.
- Active against *S. mansoni* in NMRI mouse infection model.
- Used in qualitative, quantitative, and methodological research experiments.
- Suitable for HPLC, GC, and MS applications.
Medchemexpress LLC Peramivir trihydrate | 1041434-82-5 | 98.3% | 382.45 | 25 MG
Peramivir trihydrate is a highly potent, selective, and orally active influenza virus neuraminidase (NA) inhibitor. It is intended for research use only.
- Highly potent and selective influenza virus neuraminidase (NA) inhibitor
- Has IC50 values ranging from 0.9 to 4.3 nM for nine NA subtypes
- Exhibits no toxicity to macrophages at tested concentrations
- Inhibits cytokine release in LPS-induced hPBMCs
- Inhibits LPS-induced cytokine storm and attenuates acute lung injury in mice
- Prolongs survival in cytokine storm syndrome model mice
Medchemexpress LLC Berberine (sulfate) | 633-66-9 | 433.43 | 50 MG
Berberine sulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian, functioning as an antibiotic. It induces reactive oxygen species (ROS) generation, inhibits DNA topoisomerase, and possesses antineoplastic properties. The sulfate form of berberine is noted to improve its bioavailability.
- An alkaloid isolated from the Chinese herbal medicine Huanglian.
- Functions as an antibiotic.
- Induces reactive oxygen species (ROS) generation.
- Exhibits antineoplastic properties.
- Inhibits DNA topoisomerase.
- Sulfate form improves bioavailability.
Medchemexpress LLC Celecoxib (Standard) | 169590-42-5 | 99.97% | C17H14F3N3O2S | 100 MG
Celecoxib (Standard) is the analytical standard of Celecoxib, intended for research and analytical applications. It is a selective non-steroidal anti-inflammatory drug (NSAID) and a selective COX-2 inhibitor with an IC50 of 40 nM. This compound is an analytical standard used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Analytical standard of Celecoxib
- Intended for research and analytical applications
- Selective non-steroidal anti-inflammatory drug (NSAID)
- Selective COX-2 inhibitor with an IC50 of 40 nM
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
![Medchemexpress LLC 2-butenamide, n-[4-[(4-chloro-3-fluorophenyl)amino]-7-[(3S)-tetrahydro-3-furanyloxy]-6-quinazolinyl] | 2475094-87-0 | 5mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000267580.png-250.jpg)
Medchemexpress LLC 2-butenamide, n-[4-[(4-chloro-3-fluorophenyl)amino]-7-[(3S)-tetrahydro-3-furanyloxy]-6-quinazolinyl] | 2475094-87-0 | 5mg
Afatinib impurity 33 is an impurity of Afatinib (HY-10261)
Apexbio Technology LLC Meloxicam (Mobic) 71125-38-7 10mM (in 1mL DMSO)
Meloxicam (CAS 71125-38-7) commercially known as Mobic is a nonsteroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2 (COX-2) thereby interfering with prostaglandin synthesis and mitigating inflammation and pain Its pharmacological activity against COX-2 reduces symptoms associated with rheumatoid arthritis juvenile rheumatoid arthritis and osteoarthritis such as joint pain stiffness and swelling As a COX-2 preferential inhibitor meloxicam is widely utilized as a reference compound in biomedical research examining inflammatory signaling pathways and arthritis-related disease models
Medchemexpress LLC Larotrectinib | 1223403-58-4 | 99.9% | 50 MG
Larotrectinib (LOXO-101) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, demonstrating low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C). This product is intended for research and analytical applications.
- Selective inhibitor of TRK family receptors
- ATP-competitive mechanism of action
- Inhibits TRKA, B, and C isoforms
- Exhibits antiproliferative activity against various TRK fusion and mutant cell lines
- For research use only
![Medchemexpress LLC 2-[3-[(E)-hydroxyiminomethyl]-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid | 1350352-70-3 | MFCD31807379 | 98.2% | C16H18N2O4S | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261982.png-250.jpg)
Medchemexpress LLC 2-[3-[(E)-hydroxyiminomethyl]-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid | 1350352-70-3 | MFCD31807379 | 98.2% | C16H18N2O4S | 10MG
Febuxostat impurity 7 is an analytical reference standard representing a specific impurity of febuxostat (CAS 1350352-70-3). It is supplied as a characterized solid for research and analytical applications including impurity profiling, method development, and quality control. The compound has molecular formula C16H18N2O4S and molecular weight 334.39.
- High purity (98.2%).
- Characterized identity for reliable reference standard use.
- Suitable for analytical methods such as HPLC and LC-MS.
- Intended for impurity profiling, method development, and quality control.
- Provided as a stable solid for laboratory handling and storage.
Sigma Aldrich Fine Chemicals Biosciences Zolmitriptan Related Compound E United States Pharmacopeia (USP) Reference Standard | 251451-30-6 | 25MG
Zolmitriptan Related Compound E United States Pharmacopeia (USP) Reference Standard | Mol Wt: 303.36 | 251451-30-6 | 25MG
Selleck Chemical LLC SB743921 HCl 50mg 940929-33-9
SB743921 is a kinesin spindle protein (KSP) inhibitor with Ki of 0.1 nM, almost no affinity to MKLP1, Kin2, Kif1A, Kif15, KHC, Kif4 and CENP-E. Phase 1/2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Apexbio Technology LLC Felodipine 72509-76-3 10mM (in 1mL DMSO)
Felodipine (CAS 72509-76-3) is a dihydropyridine derivative that acts as a selective inhibitor of L-type calcium channels It binds selectively to L-type voltage-gated Ca channels and inhibits calcium influx displaying an IC50 of approximately 0 15 nM In biomedical research Felodipine is predominantly used to study calcium channel-mediated cellular processes including vascular smooth muscle contraction cardiovascular physiology and calcium signaling pathways
Medchemexpress LLC Flurbiprofen | 5104-49-4 | 100.0% | 244.26 g/mol | C15H13FO2 | 1 ML
Flurbiprofen is a nonsteroidal anti-inflammatory research reagent that functions as a non-selective cyclooxygenase (COX) inhibitor. It is used in studies of inflammation, pain signaling, and certain cancer research applications. Supplied as a 10 mM solution (1 mL), the material is intended for laboratory research.
- Acts as a non-selective COX inhibitor.
- Used for inflammation, analgesia, and cancer-related research.
- High purity (99.98% by LCMS).
- Molecular weight 244.26 g/mol; formula C15H13FO2.
- CAS 5104-49-4.
- Store in solvent at -80°C (long term) or -20°C (up to 1 year).
Sigma Aldrich Fine Chemicals Biosciences STX64 >=98% (HPLC) | 288628-05-7 | MFCD12912443 | 5MG
STX64 >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 309.34 | 288628-05-7 | MFCD12912443 | 5MG
Sigma Aldrich Fine Chemicals Biosciences Cetirizine Related Compound B United States Pharmacopeia (USP) Reference Standard | 108983-83-1 | 25MG
Cetirizine Related Compound B United States Pharmacopeia (USP) Reference Standard | Mol Wt: 369.33 | 108983-83-1 | 25MG